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Orlipastat belongs to the lipase inhibitor class, primarily used for weight management. Alternatives with similar active ingredients include cetilistat (another lipase blocker) or orlistat (the parent compound). Generic orlistat 60 mg is widely available as a cost-effective substitute, often marketed under names like Alli or Xenical. Consult a healthcare provider to compare efficacy and side effects.

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Orlipastat inhibits dietary fat absorption, unlike stimulant-based appetite suppressants (e.G. phentermine) or GLP-1 agonists (e.G. semaglutide). Its side effects-such as oily stools-are less severe than those of prescription alternatives. For mild to moderate weight management, it's a practical choice, but individual responses vary.

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Clinical studies indicate that prolonged use can lead to minor vitamin deficiencies due to reduced fat absorption. Patients are advised to take multivitamins and monitor lipid levels. Alternatives like green tea extract or conjugated linoleic acid (CLA) may offer milder, non-pharmaceutical support.

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Orlipastat suits individuals with a BMI ≥25 who struggle with dietary fat intake. For obesity-related conditions (e.G. hypertension or diabetes), it complements lifestyle changes but isn't a standalone solution. Those with chronic pancreatitis or cholestasis should avoid it. Patients with food allergies or malabsorption syndromes must consult a specialist. Adolescents and pregnant women require medical supervision. Always pair Orlipastat with a balanced diet and exercise for sustainable results. If cost is a barrier, explore generic orlistat or subsidized health programs.

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